Gene Lookup
The genes behind your polygenic (more than one gene) scores, each with a plain-language summary. Search a gene symbol, a trait, or a keyword.
A
ABCA1Lipid TransportHelps move cholesterol out of cells and into the bloodstream for clearing.
ATP Binding Cassette Subfamily A Member 1
ABCB1DetoxificationActs as a security pump that helps push unwanted substances out of your cells.
ATP Binding Cassette Subfamily B Member 1
ABCC2Liver DetoxHelps the liver move metabolic waste products into the bile for disposal.
ATP Binding Cassette Subfamily C Member 2
ABCC9Sleep NeedLinked to how much sleep you naturally need.
ATP Binding Cassette Subfamily C Member 9
ABCG2Urate RegulationManages how your body clears uric acid to prevent buildup in the joints.
ATP Binding Cassette Subfamily G Member 2
ABCG8Cholesterol RemovalHelps your liver and gut move cholesterol out of the body.
ATP Binding Cassette Subfamily G Member 8
ACEBlood PressureHelps regulate blood pressure and tilts muscles toward power or endurance.
Angiotensin Converting Enzyme
ACORE1Fatty Acid OxidationHelps break down long-chain fats so your body can use them for energy.
Acyl-CoA Oxidase 1
ACTN3Muscle FunctionTells you if your muscles are built for explosive speed and power.
Alpha-Actinin-3
ADASleep QualityHelps clear adenosine, the chemical that builds up and makes you sleepy.
Adenosine Deaminase
ADCY3Satiety SignalHelps the fullness signal reach your brain on time.
Adenylate Cyclase 3
ADCY5Blood SugarHelps your body regulate blood sugar between meals.
Adenylate Cyclase 5
ADD1Sodium HandlingInfluences how your kidneys handle salt and its impact on your blood pressure.
Adducin 1
ADH1BAlcohol MetabolismHelps your body convert alcohol into its first by-product; some versions do it very fast.
Alcohol Dehydrogenase 1B
ADIPOQMetabolic HormoneA hormone from fat cells that helps your body manage sugar and burn fat.
Adiponectin
ADORA2ACaffeine ResponseWhere caffeine plugs in to keep you feeling alert instead of drowsy.
Adenosine A2a Receptor
ADRB1Heart HealthReceives adrenaline's signal in your heart and sets how fast your heart rate responds to exertion.
Adrenoceptor Beta 1
ADRB2Fat MobilizationControls how easily your body switches over to burning stored fat for fuel.
Adrenoceptor Beta 2
ADRB3Helps your body generate heat and burn energy when you are cold or active.
GAderneneosc Adrenoceptor Beta 3
AGTBlood PressureA master signal that helps your body regulate long-term blood pressure levels.
Angiotensinogen
AGTR1Vascular HealthControls how your blood vessels tighten or relax to manage blood flow.
Angiotensin II Receptor Type 1
AGXT2Creatine ProductionLinked to how your body makes creatine for quick bursts of effort.
Alanine-Glyoxylate Aminotransferase 2
AHREnvironmental DetoxSenses environmental pollutants and tells your liver to start cleaning them.
Aryl Hydrocarbon Receptor
ALDH2Alcohol MetabolismThe main worker that clears out the toxic byproducts of alcohol.
Aldehyde Dehydrogenase 2
ALPLVitamin B6 LevelsHelps set how much active vitamin B6 your blood carries and supports bone building.
Alkaline Phosphatase, Biomineralization Associated
AMELXTooth EnamelProvides the building blocks for the hard outer layer of your teeth.
Amelogenin X-Linked
AMPD1Muscle EnergyHelps your muscles recycle energy during intense exercise.
Adenosine Monophosphate Deaminase 1
AMY1Carb DigestionDetermines how well you break down bread and pasta while you chew.
Amylase Alpha 1 (Salivary)
ANKK1Reward SignalingWorks with dopamine to determine how much you crave rewarding foods.
Ankyrin Repeat And Kinase Domain Containing 1
AOC1Histamine ClearanceHelps break down histamine from aged and fermented foods like wine and cheese.
Amine Oxidase Copper Containing 1
APOA2Fat ResponseInfluences how your body reacts to saturated fats like butter and red meat.
Apolipoprotein A2
APOA4Fat AbsorptionHelps carry fats after a meal and signals fullness.
Apolipoprotein A4
APOA5Triglyceride ControlHelps clear fats (triglycerides) out of your blood after a greasy meal.
Apolipoprotein A5
APOBLipid TransportThe main building block for the "bad" cholesterol that travels in your blood.
Apolipoprotein B
APOC3Lipid ClearanceControls how fast or slow your body clears fats out of your bloodstream.
Apolipoprotein C3
APOECholesterol BalanceManages how your brain and body handle fats and repair cell membranes.
Apolipoprotein E
ASIPSkin PigmentHelps balance the type of pigment your skin makes.
Agouti Signaling Protein
ATP2B1Mineral BalanceHelps manage calcium levels to keep your blood vessels healthy.
ATPase Plasma Membrane Ca2+ Transporting 1
AURE1Cellular ResponseInvolved in how cells respond to specific growth and nutrient signals.
Auxin Response Element 1
B
BCHEToxin ClearanceClears out specific pesticides and anesthetic chemicals from your system.
Butyrylcholinesterase
BCO1Vitamin A ConversionDetermines if you can turn orange veggies (beta-carotene) into active Vitamin A.
Beta-Carotene Oxygenase 1
BDKRB2Vessel HealthHelps widen blood vessels and shapes how they adapt to training.
Bradykinin Receptor B2
BDNFBrain HealthHelps your brain cells grow, stay healthy, and manage appetite signals.
Brain Derived Neurotrophic Factor
BDNF-ASGene RegulationA "dimmer switch" that controls how much BDNF your brain produces.
BDNF Antisense RNA
BHLHE41Sleep NeedRare versions are linked to needing less sleep than most people.
Basic Helix-Loop-Helix Family Member E41
BHMTMethylation MakerHelps recycle homocysteine using betaine, a backup to the folate route.
Betaine-Homocysteine S-Methyltransferase
BNC2Skin PigmentLinked to freckling and skin color.
Basonuclin 2
BTBD9Sleep QualityLinked to restless legs and broken sleep.
BTB Domain Containing 9
C
CADM2Appetite ControlLinked to how strongly food cues pull at you.
Cell Adhesion Molecule 2
CASRMineral SensingActs as the thermostat that monitors how much calcium is in your blood.
Calcium Sensing Receptor
CATCell StabilityAn enzyme that clears hydrogen peroxide, a by-product of hard exercise and everyday metabolism.
Catalase
CBSSulfur MetabolismConverts homocysteine into antioxidants like glutathione.
Cystathionine Beta-Synthase
CD36Fat EntryHelps your tongue and cells detect and take up fat.
CD36 Molecule
CETPCholesterol SwapManages the exchange of cholesterol between "good" and "bad" particles.
Cholesteryl Ester Transfer Protein
CHDHCholine MakerHelps turn choline into betaine.
Choline Dehydrogenase
CHKACholine MakerHelps your cells put choline to use.
Choline Kinase Alpha
CKMMuscle EnergyHelps muscle cells recycle quick energy during effort.
Creatine Kinase, M-Type
CLDN16Kidney FilteringHelps your kidneys hold onto magnesium instead of flushing it away.
Claudin 16
CLDN19Mineral TransportWorks with Claudin 16 to ensure your body keeps enough magnesium and calcium.
Claudin 19
CLEC16AImmune BalanceLinked to how your immune system keeps itself in check.
C-Type Lectin Domain Containing 16A
CLOCKBiological TimingSets your internal rhythm for sleep, hunger, and energy throughout the day.
Circadian Locomotor Output Cycles Kaput
CNR1Bliss SignalingControls how you feel pleasure and relaxation from food and stress-relief.
Cannabinoid Receptor 1
COBLL1Insulin SignalLinked to how much insulin your body needs for a meal.
Cordon-Bleu WH2 Repeat Protein Like 1
COL1A1Connective TissueProvides the strength and structure for your bones, skin, and tendons.
Collagen Type I Alpha 1
COL1A2Connective TissueHelps build collagen in bone, teeth and skin.
Collagen Type I Alpha 2 Chain
COL3A1Connective TissueHelps build the collagen that gives skin, vessels and ligaments their strength.
Collagen Type III Alpha 1 Chain
COL5A1Connective TissueHelps build the collagen scaffolding in tendons and ligaments.
Collagen Type V Alpha 1 Chain
COMTNeurotransmitter DetoxTidies up stress chemicals in the brain so you can stay calm and focused.
Catechol-O-Methyltransferase
COQ2Energy DeliveryHelps your cells make CoQ10 for energy production.
Coenzyme Q2, Polyprenyltransferase
CPIron TransportThe main protein that carries copper and helps your body use iron properly.
Ceruloplasmin
CPS1Urea CycleHelps your body clear out the waste created when you eat animal protein.
Carbamoyl-Phosphate Synthase 1
CREB1Cell SignalingA signaling switch that helps your body adapt to training.
cAMP Responsive Element Binding Protein 1
CRHR1Stress ResponseControls how your body reacts to sudden pressure or stressful events.
Corticotropin Releasing Hormone Receptor 1
CRPInflammation MarkerA signal the liver sends out when your body is experiencing inflammation.
C-Reactive Protein
CRY1Biological TimingHelps your body clock keep time; some versions run a little long.
Cryptochrome Circadian Regulator 1
CRY2Biological TimingA body-clock gene that also links your daily rhythm to blood sugar.
Cryptochrome Circadian Regulator 2
CUBNVitamin AbsorptionHelps your small intestine grab Vitamin B12 out of the food you eat.
Cubilin
CYP11B2Fluid BalanceHelps produce the hormone that tells your body to hold onto salt and water.
Cytochrome P450 Family 11 Subfamily B Member 2
CYP19A1Hormone BalanceConverts androgens into estrogens to keep your hormones in balance.
Cytochrome P450 Family 19 Subfamily A Member 1
CYP1A1Environmental DetoxHelps your body process compounds from smoke and charred food.
Cytochrome P450 Family 1 Subfamily A Member 1
CYP1A2Caffeine MetabolismDetermines if you are a fast or slow coffee drinker.
Cytochrome P450 Family 1 Subfamily A Member 2
CYP1B1Hormone PrepHelps your body process hormones and some environmental compounds.
Cytochrome P450 Family 1 Subfamily B Member 1
CYP24A1Vitamin D ProcessingHelps your body break down active vitamin D.
Cytochrome P450 Family 24 Subfamily A Member 1
CYP27B1Vitamin D ActivationTurns the Vitamin D from the sun and food into its "active" working form.
Cytochrome P450 Family 27 Subfamily B Member 1
CYP2E1Liver DetoxA liver enzyme that processes alcohol and small industrial chemicals.
Cytochrome P450 Family 2 Subfamily E Member 1
CYP2R1Vitamin D ProcessingThe first worker in the liver that begins processing Vitamin D.
Cytochrome P450 Family 2 Subfamily R Member 1
CYP3A4Liver ProcessingHelps your liver break down many of the substances you take in.
Cytochrome P450 Family 3 Subfamily A Member 4
CYP4F2Vitamin K BalanceHelps manage levels of Vitamin K and Vitamin E in your system.
Cytochrome P450 Family 4 Subfamily F Member 2
CYP7A1Bile Acid SynthesisConverts cholesterol into bile to help you digest fats and clear waste.
Cytochrome P450 Family 7 Subfamily A Member 1
D
DBHChemical ConversionConverts dopamine into norepinephrine to manage your "fight or flight" response.
Dopamine Beta-Hydroxylase
DENND1AHormone BalanceLinked to hormone patterns that affect cycles.
DENN Domain Containing 1A
DHCR7Vitamin D SynthesisHelps the skin start making Vitamin D when you are out in the sun.
7-Dehydrocholesterol Reductase
DHFRFolate MetabolismRecycles used folate so your cells can use it for DNA repair and energy.
Dihydrofolate Reductase
DIO1Thyroid ConversionConverts the "storage" version of thyroid hormone into the "active" version.
Deiodinase Type 1
DIO2Active ThyroidActivates thyroid hormone inside your cells to control your metabolic rate.
Deiodinase Type 2
DRD2Reward SignalingDetermines how much pleasure you get from food, exercise, and hobbies.
Dopamine Receptor D2
E
EDN1Vascular ToneA signal that tells your blood vessels to tighten, raising blood pressure.
Endothelin 1
EGLN1Oxygen SensingAn oxygen sensor that sets how your body reacts to low oxygen.
Egl-9 Family Hypoxia Inducible Factor 1
ELOVL2Omega ConversionHelps turn plant omega-3 into longer forms your body uses.
ELOVL Fatty Acid Elongase 2
EPAS1Oxygen SensingHelps your body use oxygen well at high effort or high altitude.
Endothelial PAS Domain Protein 1
EPHX1Toxin NeutralizerHelps break down specific environmental toxins and pollutants in the liver.
Epoxide Hydrolase 1
ESR1Estrogen SensingTells your cells how to respond to estrogen signals for bone and heart health.
Estrogen Receptor 1
ESR2Estrogen SensingHelps your cells respond to estrogen.
Estrogen Receptor 2
F
FAAHBliss ManagementBreaks down the "bliss molecule" in your brain to regulate mood and hunger.
Fatty Acid Amide Hydrolase
FABP1Fat AbsorptionHelps carry fats around inside liver cells.
Fatty Acid Binding Protein 1
FABP2Fat AbsorptionDetermines how quickly your gut absorbs fats from your meals.
Fatty Acid Binding Protein 2
FADS1Omega ConversionHelps turn plant-based fats (like flax) into the brain-healthy fish oil (EPA).
Fatty Acid Desaturase 1
FADS2Omega ProcessingWorks with FADS1 to build long-chain healthy fats for your brain and heart.
Fatty Acid Desaturase 2
FGF21Sugar PreferenceHelps regulate your cravings for sugar and your preference for sweets.
Fibroblast Growth Factor 21
FKBP5Stress ResponseHelps set how your body winds down after stress.
FKBP Prolyl Isomerase 5
FLGBarrier ProtectionHelps build your skin's protective moisture barrier.
Filaggrin
FMO3Chemical ConversionHelps convert strong-smelling compounds from food so they do not linger on your breath or skin.
Flavin Containing Dimethylaniline Monoxygenase 3
FOLH1Folate IntakeHelps your gut absorb folate from food.
Folate Hydrolase 1
FOXE1Thyroid DevelopmentInvolved in the development and health of your thyroid gland.
Forkhead Box E1
FSHBHormone BalanceHelps make the hormone that drives the ovarian cycle.
Follicle Stimulating Hormone Subunit Beta
FTOAppetite ControlControls how loud your hunger signals feel throughout the day.
Fat Mass And Obesity-Associated
FUT2Microbiome HealthDetermines which healthy bacteria can live and thrive in your gut.
Fucosyltransferase 2
G
G6PC2Sugar SensingHelps set your "fasting" blood sugar level when you haven't eaten.
Glucose-6-Phosphatase Catalytic Subunit 2
G6PDCell StabilityProtects red blood cells from damage and supports your body's energy chemistry.
Glucose-6-Phosphate Dehydrogenase
GABRA2Calming SignalsPart of the brain's main calming system, which alcohol also acts on.
Gamma-Aminobutyric Acid Type A Receptor Subunit Alpha2
GAD2Calming SignalsHelps turn an "exciting" brain chemical into a "calming" one (GABA).
Glutamate Decarboxylase 2
GCVitamin D CarrierCarries Vitamin D through your blood to the cells that need it.
Vitamin D Binding Protein
GCH1Pain SignalingHelps your nerves make the chemicals that tune pain signals.
GTP Cyclohydrolase 1
GCKLiver Sugar-SenseThe liver's blood-sugar sensor.
Glucokinase
GCKRSugar StorageHelps your liver decide whether to store sugar or burn it for energy.
Glucokinase Regulator
GCLCDetox DefenseHelps your cells make glutathione, their main antioxidant.
Glutamate-Cysteine Ligase Catalytic Subunit
GDF5Joint HealthHelps build and maintain joint cartilage.
Growth Differentiation Factor 5
GGCXVitamin K FunctionHelps Vitamin K do its job in bone health and blood clotting.
Gamma-Glutamyl Carboxylase
GIPRInsulin SignalTells your body to release insulin in response to a meal.
Gastric Inhibitory Polypeptide Receptor
GLP1RSatiety SignalHelps you feel full after a meal and manages blood sugar.
Glucagon Like Peptide 1 Receptor
GNB3Cell SignalingAffects how your cells respond to signals for heart rate and metabolism.
G Protein Subunit Beta 3
GNPDA2Weight RegulationLinked to body weight set point.
Glucosamine-6-Phosphate Deaminase 2
GNRHRHormone MasterA master signal for the hormones that control your reproductive health.
Gonadotropin Releasing
GPX1Detox DefenseUses selenium to protect your cells from oxidative stress and damage.
Glutathione Peroxidase 1
GPX4Selenium CarrierA selenium-based antioxidant enzyme that protects cell membranes.
Glutathione Peroxidase 4
GRIK1Nerve SignalingInvolved in the fast signals between your brain cells.
Glutamate Ionotropic Receptor Kainate Type 1
GSTO1Heavy Metal DetoxHelps your body clear out specific heavy metals and environmental toxins.
Glutathione S-Transferase Omega 1
GSTO2Vitamin C UseLinked to how quickly your body uses up vitamin C.
Glutathione S-Transferase Omega 2
GSTP1General DetoxOne of your body's main tools for clearing pollutants and smoke.
Glutathione S-Transferase Pi 1
H
HCN4Heart HealthHelps set your heart's natural pacemaker rhythm.
Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4
HCRTR2Wakefulness SignalReceives the brain's wake-up signal that keeps you alert during the day.
Hypocretin Receptor 2
HERC2Skin PigmentA control region near the pigment gene OCA2 that strongly affects eye and skin color.
HECT And RLD Domain Containing E3 Ubiquitin Protein Ligase 2
HFEIron ManagerControls how much iron your body absorbs from the food you eat.
Homeostatic Iron Regulator
HIF1AOxygen SensingHelps your body adjust when oxygen runs low during hard effort.
Hypoxia Inducible Factor 1 Subunit Alpha
HLA-BVirus DefenseHelps your immune system identify and attack viruses and bacteria.
Major Histocompatibility Complex, Class I, B
HLA-DQA1Protein ScanningScans proteins like gluten to see if they are "friends" or "enemies.".
Major Histocompatibility Complex, Class II, DQ Alpha 1
HMGCRCholesterol MakerThe main "on/off" switch for your body's own cholesterol production.
HMG-CoA Reductase
HNF1ASugar SensingA control gene for how the liver and pancreas handle sugar and fats.
HNF1 Homeobox A
HNMTHistamine ClearanceHelps clear histamine inside your cells.
Histamine N-Methyltransferase
HTR1AMood BalanceListens for the "feel-good" serotonin signal to help you feel calm.
5-Hydroxytryptamine Receptor 1A
HTR2AMental PoiseAffects your brain's sensitivity to mood signals and stress.
5-Hydroxytryptamine Receptor 2A
I
IGF1Growth ControlA growth signal that helps muscle and bone grow and repair.
Insulin Like Growth Factor 1
IGF2Growth ControlA growth signal that helps muscle develop and repair.
Insulin Like Growth Factor 2
IL13Inflammation ResponseAn immune signal involved in skin and airway allergies.
Interleukin 13
IL18R1Inflammation ResponseReceives an immune signal involved in skin and airway inflammation.
Interleukin 18 Receptor 1
IL1RL1Inflammation ResponseReceives an immune alarm signal involved in allergies.
Interleukin 1 Receptor Like 1
IL6Inflammatory SignalA signal that tells your body to start an immune response or fever.
Interleukin 6
IL6RInflammation ResponseReceives an immune signal that drives inflammation.
Interleukin 6 Receptor
INSRInsulin SignalThe doorway that lets insulin tell your cells to take up sugar.
Insulin Receptor
IRF4Skin PigmentHelps set how much natural color your skin makes.
Interferon Regulatory Factor 4
IRS1Insulin ConnectionHelps the insulin signal get from the blood into your cells.
Insulin Receptor Substrate 1
K
KCNJ11Insulin PulseControls how your pancreas releases a pulse of insulin.
Potassium Inwardly Rectifying Channel Subfamily J Member 11
KCNQ1Energy RhythmHelps maintain a steady rhythm for insulin release and heart health.
Potassium Voltage-Gated Channel Subfamily Q Member 1
KCNS1Pain SignalingA nerve channel that influences how strongly you notice aches.
Potassium Voltage-Gated Channel Modifier Subfamily S Member 1
KCTD15Weight RegulationInvolved in how your brain manages long-term weight and hunger.
Potassium Channel Tetramerization Domain Containing 15
KIF3ABarrier ProtectionLinked to how well your skin and airways hold up against irritation.
Kinesin Family Member 3A
KLMineral BalanceHelps balance phosphorus, calcium and vitamin D.
Klotho
KLBHormone BalanceHelps your body respond to a hormone that influences food choices and sweet cravings.
Klotho Beta
KLK4Tooth EnamelHelps form strong tooth enamel.
Kallikrein Related Peptidase 4
L
LCTDairy DigestionThe enzyme that lets you digest the sugar in milk and cheese.
Lactase
LEPFullness HormoneThe hormone sent by your fat cells to tell your brain you are full.
Leptin
LEPRLeptin SensingThe part of your brain that "hears" the fullness signal from your fat cells.
Leptin Receptor
LIN28BHormone BalanceLinked to when puberty starts and adult height.
Lin-28 Homolog B
LIPCFat ClearingHelps the liver clear out "good" cholesterol and triglycerides.
Lipase C, Hepatic Type
LPAHeart HealthA specific type of cholesterol particle that can impact artery health.
Apolipoprotein(a)
LPLEnergy DeliveryHelps move fats from your blood into your muscles to be used as energy.
Lipoprotein Lipase
LRP5Bone BuildingHelps your bones build and keep their strength.
LDL Receptor Related Protein 5
LRRC32Immune BalanceHelps keep your immune system from over-reacting.
Leucine Rich Repeat Containing 32
M
MAFFStress ResponseHelps protect your cells from stress and inflammation.
MAF BZIP Transcription Factor F
MAOAChemical RecyclerBreaks down chemicals like serotonin and dopamine to keep them balanced.
Monoamine Oxidase A
MAP2K5Weight RegulationLinked to resting calorie burn and body weight.
Mitogen-Activated Protein Kinase Kinase 5
MAT1AMethylation MakerHelps create SAMe, the body's main tool for DNA repair and health.
Methionine Adenosyltransferase 1A
MBL2Virus DefensePart of your first-line immune defenses against germs.
Mannose Binding Lectin 2
MC1RSkin PigmentHelps decide how your skin makes pigment and responds to the sun.
Melanocortin 1 Receptor
MC4RSatiety IntegrationThe master switch that turns off hunger once you've had enough.
Melanocortin 4 Receptor
MCM6Lactase ControlThe "on/off" switch that tells your LCT gene to keep working into adulthood.
Minichromosome Maintenance Complex Component 6
MCM8DNA ProtectionHelps repair DNA and is linked to timing of menopause.
Minichromosome Maintenance 8 Homologous Recombination Repair Factor
MEIS1Sleep QualityLinked to how easily you fall asleep and how restless your legs feel at night.
Meis Homeobox 1
MMP3Connective TissueHelps your body renew tendons and other soft tissue.
Matrix Metallopeptidase 3
MOCOSMineral BalanceHelps your body use the trace mineral molybdenum.
Molybdenum Cofactor Sulfurase
MSTNMuscle GrowthActs as a brake on muscle growth.
Myostatin
MTHFD1Folate ProcessingInvolved in the complicated steps of using B-vitamins to build DNA.
Methylenetetrahydrofolate Dehydrogenase 1
MTHFRFolate MetabolismThe main worker that turns inactive folate into the "active" form your cells use.
Methylenetetrahydrofolate Reductase
MTNR1BSleep/Sugar LinkConnects your sleep rhythm with how your body handles sugar at night.
Melatonin Receptor 1B
MTORGrowth ControlThe main switch that tells your cells when to grow and build muscle.
Mechanistic Target Of Rapamycin Kinase
MTRB12 UtilizationUses Vitamin B12 to keep your homocysteine and energy levels in check.
5-Methyltetrahydrofolate-Homocysteine Methyltransferase
MTRRB12 RechargerRecharges your Vitamin B12 so it can keep working for your cells.
5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase
MTTPFat AbsorptionHelps package fats so they can travel in your blood.
Microsomal Triglyceride Transfer Protein
MUC1Barrier ProtectionProvides a protective slippery coating for your gut and lungs.
Mucin 1, Cell Surface Associated
MUTB12 MetabolismUses Vitamin B12 to help you turn proteins and fats into energy.
Methylmalonyl-CoA Mutase
N
NADSYN1NAD ProductionHelps create NAD+, a vital molecule for cellular energy and aging.
NAD Synthetase 1
NAPRTVitamin B3 UseHelps your body use Vitamin B3 to protect your cells.
Nicotinate Phosphoribos
NAT2Liver ClearanceHelps clear environmental substances and smoke from your body.
N-Acetyltransferase 2
NBPF3Vitamin B6 LevelsInfluences how high or low your Vitamin B6 levels stay in your blood.
NBPF Member 3
NEDD4LSodium HandlingHelps your kidneys regulate how much salt you hold on to.
NEDD4 Like E3 Ubiquitin Protein Ligase
NEGR1Weight RegulationLinked to how strongly your body defends its usual weight.
Neuronal Growth Regulator 1
NFE2L2Detox DefenseThe master switch that turns on your cells' own antioxidant defenses.
Nuclear Factor, Erythroid 2 Like 2
NOS3Vessel HealthCreates nitric oxide, which helps your blood vessels relax and open up.
Nitric Oxide Synthase 3
NPYHunger PromotionThe internal voice that yells "eat now" when you are stressed or empty.
Neuropeptide Y
NQO1Detox DefenseHelps protect your cells from reactive chemicals and supports heart health.
NAD(P)H Quinone Dehydrogenase 1
NR3C1Cortisol ListenerTells your cells how to respond to the stress hormone cortisol.
Nuclear Receptor Subfamily 3 Group C Member 1
NR3C2Fluid RegulationHelps your kidneys balance salt and water to manage blood pressure.
Nuclear Receptor Subfamily 3 Group C Member 2
NRXN3Appetite ControlLinked to how strongly cravings and food cues pull at you.
Neurexin 3
O
OCA2Skin PigmentA key gene for the amount of pigment in skin and eyes.
OCA2 Melanosomal Transmembrane Protein
OPRM1Pleasure SensingControls how you feel pleasure and relief from things like exercise or food.
Opioid Receptor Mu 1
OXTRSocial BondInfluences how you respond to the "cuddle hormone" for trust and social bond.
Oxytocin Receptor
P
PARP1DNA ProtectionSenses damage in your DNA and calls in the repair team to fix it.
Poly(ADP-Ribose) Polymerase 1
PBX4Digestive HealthLinked to how prone you are to acid reflux.
PBX Homeobox 4
PCSK1Hormone PrepPrepares hormones like insulin and satiety signals so they can do their job.
Proprotein Convertase Subtilisin/Kexin Type 1
PCSK9Cholesterol RemovalRegulates how many cholesterol "recycling bins" your liver has.
Proprotein Convertase Subtilisin/Kexin Type 9
PDE4BSleep NeedLinked to your natural sleep length and brain signaling.
Phosphodiesterase 4B
PDE8BThyroid ControlHelps regulate the signals that tell your thyroid how hard to work.
Phosphodiesterase 8B
PEMTCholine MakerHelps your liver create its own choline to protect your brain and liver.
Phosphatidylethanolamine N-Methyltransferase
PER2Biological TimingA core body-clock gene that helps set when you feel sleepy and when you wake up.
Period Circadian Regulator 2
PER3Biological TimingHelps set whether you are naturally a morning or evening person.
Period Circadian Regulator 3
PNPLA3Liver fat-StorageManages how much fat your liver stores; prevents "fatty liver.".
Patatin Like Phospholipase Domain Containing 3
PON1Toxin ClearanceHelps your body break down certain pesticides and protects fats in your blood from damage.
Paraoxonase 1
PPARAFasting MetabolismTurns on your fat-burning engines when you go for long periods without food.
Peroxisome Proliferator Activated Receptor Alpha
PPARDEndurance MuscleHelps build and fuel the muscle fibers used for long-distance exercise.
Peroxisome Proliferator Activated Receptor Delta
PPARGEnergy PartitioningDecides if energy gets stored in fat cells or used for muscle repair.
Peroxisome Proliferator Activated Receptor Gamma
PPARGC1AEndurance MuscleHelps your muscles build more energy-making machinery when you train.
PPARG Coactivator 1 Alpha
PTBP1RNA ProcessingHelps edit the "messages" from your DNA to ensure they are clear.
Polypyrimidine Tract Binding Protein 1
PTGS2Inflammation SwitchThe main switch that triggers inflammation and pain (also known as COX-2).
Prostaglandin-Endoperoxide Synthase 2
PTPN1Insulin BrakeActs as the "brake" on your insulin signal to keep it from over-working.
Protein Tyrosine Phosphatase Non-Receptor Type 1
PTPRDSleep QualityLinked to restless feelings in the legs at night.
Protein Tyrosine Phosphatase Receptor Type D
R
RGS16Biological TimingA body-clock related gene that nudges you toward being a morning or evening person.
Regulator Of G Protein Signaling 16
S
SCARB1HDL DeliveryHelps your liver grab "good" cholesterol and clear it out.
Scavenger Receptor Class B Member 1
SCDFat MetabolismHelps your body turn saturated fats into other fats it can store or use.
Stearoyl-CoA Desaturase
SCN9APain SignalingA nerve channel that helps set how sharply you feel pain.
Sodium Voltage-Gated Channel Alpha Subunit 9
SCNN1BSodium HandlingPart of the channel that lets your kidneys reabsorb salt.
Sodium Channel Epithelial 1 Subunit Beta
SCNN1GSodium HandlingPart of the channel that lets your kidneys reabsorb salt.
Sodium Channel Epithelial 1 Subunit Gamma
SEC16BWeight RegulationLinked to body weight and fat storage.
SEC16 Homolog B
SELENOPSelenium CarrierCarries selenium around your body.
Selenoprotein P
SEPP1Selenium CarrierCarries the antioxidant selenium to the cells that need protection.
Selenoprotein P
SH2B1Weight ControlHelps the signals for insulin and leptin reach their destination.
SH2B Adaptor Protein 1
SHBGHormone BalanceThe protein that carries sex hormones in your blood.
Sex Hormone Binding Globulin
SHMT1DNA BuildingHelps move B-vitamins toward building new DNA.
Serine Hydroxymethyltransferase 1
SISugar DigestionThe enzyme that lets you digest table sugar and starch.
Sucrase-Isomaltase
SLC12A3Kidney Salt-BalanceHelps your kidneys balance salt to manage your blood pressure.
Solute Carrier Family 12 Member 3
SLC16A1Muscle EnergyHelps move lactate out of muscle cells during hard effort.
Solute Carrier Family 16 Member 1
SLC19A1Folate IntakeThe doorway that lets folate into your cells.
Solute Carrier Family 19 Member 1
SLC23A1Vitamin C IntakeHelps your kidneys and gut absorb and keep Vitamin C.
Solute Carrier Family 23 Member 1
SLC23A2Vitamin C UseHelps move Vitamin C into the specific cells that need it.
Solute Carrier Family 23 Member 2
SLC2A1Brain FuelThe main doorway that lets sugar into your brain for energy.
Solute Carrier Family 2 Member 1
SLC2A2Liver Sugar-SenseActs as a sensor in the liver and pancreas to monitor blood sugar levels.
Solute Carrier Family 2 Member 2
SLC2A9Urate RegulationHelps your kidneys control uric acid.
Solute Carrier Family 2 Member 9
SLC30A8Zinc ManagerHelps move zinc into the cells that produce insulin.
Solute Carrier Family 30 Member 8
SLC39A4Zinc ManagerHelps your gut absorb zinc.
Solute Carrier Family 39 Member 4
SLC39A8Mineral DoorA doorway for minerals like zinc and manganese to enter your cells.
Solute Carrier Family 39 Member 8
SLC44A1Choline MakerHelps bring choline into your cells.
Solute Carrier Family 44 Member 1
SLC45A2Skin PigmentHelps set how much natural color your skin makes.
Solute Carrier Family 45 Member 2
SLC5A5Iodine IntakeHelps your thyroid gland grab iodine from the blood to make hormones.
Solute Carrier Family 5 Member 5
SLC6A3Dopamine RecyclerTidies up dopamine in the brain to regulate your focus and drive.
Solute Carrier Family 6 Member 3
SLC6A4Serotonin RecyclerManages the recycling of serotonin to control your mood and appetite.
Solute Carrier Family 6 Member 4
SOD2Mitochondrial DetoxProtects your cells' energy factories from damage.
Superoxide Dismutase 2
SOD3Cell StabilityAn antioxidant enzyme that works outside your cells to calm free radicals.
Superoxide Dismutase 3
SORT1Lipid RegulationHelps the liver decide how to process and clear out cholesterol.
Sortilin 1
SOSTBone BuildingA natural brake that slows new bone formation.
Sclerostin
SRD5A2Hormone BalanceConverts testosterone into its stronger form.
Steroid 5 Alpha-Reductase 2
SULT1A1Sulfur MetabolismHelps your body attach sulfur to compounds so they can be cleared.
Sulfotransferase Family 1A Member 1
SUOXSulfite CleanerBreaks down sulfites (found in wine and dried fruit) into safe sulfate.
Sulfite Oxidase
T
TAS1R2Sweet PerceptionDetermines how sensitive you are to the taste of sugar and sweets.
Taste 1 Receptor Member 2
TAS1R3Sweet PerceptionPart of how your tongue senses sweetness.
Taste 1 Receptor Member 3
TAS2R38Bitter PerceptionDetermines if you find veggies like broccoli or kale to be very bitter.
Taste 2 Receptor Member 38
TBC1D4Sugar UptakeTells your muscle cells to open up and take in sugar during exercise.
TBC1 Domain Family Member 4
TCF7L2Insulin ControlControls how your body handles insulin after a meal.
Transcription Factor 7 Like 2
TCN1B12 MetabolismHelps carry vitamin B12 in your blood.
Transcobalamin 1
TCN2B12 MetabolismCarries vitamin B12 into your cells.
Transcobalamin 2
TFIron TransportThe protein that carries iron around your blood.
Transferrin
TFAP2BWeight RegulationLinked to body weight and where your body stores fat.
Transcription Factor AP-2 Beta
TFR2Iron SorterHelps your body monitor and manage how much iron is in circulation.
Transferrin Receptor 2
THADAHormone BalanceLinked to hormone patterns that affect cycles and blood sugar.
THADA Armadillo Repeat Containing
TLR4Inflammation SwitchA sensor that tells your immune system when bacteria are present.
Toll Like Receptor 4
TMEM18Weight RegulationLinked to body weight set point.
Transmembrane Protein 18
TMPRSS6Iron AbsorptionControls the signal that tells your body to absorb more iron.
Transmembrane Serine Protease 6
TNCConnective TissueHelps tendons, such as the Achilles, handle load.
Tenascin C
TNFInflammatory Signal Systemic InflammationA powerful signal that triggers inflammation to fight off threats. A major "fire alarm" for the whole body's immune system.
Tumor Necrosis Factor
TNFRSF11ABone BuildingReceives the signal that triggers old-bone clearing.
TNF Receptor Superfamily Member 11a
TNFRSF1BInflammation ResponseListens for the inflammation alarm and tells the cell how to react.
TNF Receptor
TNFSF11Bone BuildingSignals the cells that clear old bone.
TNF Superfamily Member 11
TPH2Mood BalanceHelps your brain make serotonin.
Tryptophan Hydroxylase 2
TRPM6Magnesium IntakeThe main doorway for magnesium to enter your gut and kidneys.
Transient Receptor Potential Cation Channel Subfamily M Member 6
TRPM7Magnesium IntakeHelps your cells take in magnesium.
Transient Receptor Potential Cation Channel Subfamily M Member 7
TRPV1Spice PerceptionDetermines how sensitive you are to "spicy heat" in foods like peppers.
Transient Receptor Potential Vanilloid 1
TSLPInflammation ResponseA skin and airway signal that can start allergic reactions.
Thymic Stromal Lymphopoietin
TYRSkin PigmentThe enzyme that kicks off pigment production.
Tyrosinase
U
UADPGenetic SegmentA specific segment of your DNA involved in metabolic pathways.
Unknown Gene Placeholder
UCP1Thermic EffectHelps your body burn some food energy as heat.
Uncoupling Protein 1
UCP2Thermic EffectHelps your body burn off extra calories as heat rather than storing them.
Uncoupling Protein 2
UMODKidney HealthProvides a protective protein that keeps your kidneys and urinary tract healthy.
Uromodulin
V
VDRVitamin D ListenerTells your cells how to respond to Vitamin D for bone and immune health.
Vitamin D Receptor
VEGFAVessel BuilderHelps build new blood vessels to improve blood flow to tissues.
Vascular Endothelial Growth Factor A
VKORC1Vitamin K RecyclingRecycles Vitamin K so your blood can clot and bones stay strong.
Vitamin K Epoxide Reductase Complex Subunit 1
VLDLRLipid EntryHelps move specific fat particles into your brain and other tissues.
Very Low Density Lipoprotein Receptor
W
WFS1Cell StabilityHelps manage stress inside the parts of your cells that make proteins.
Wolframin ER Transmembrane Glycoprotein
WNK1Sodium HandlingHelps your kidneys balance salt and potassium.
WNK Lysine Deficient Protein Kinase 1
WNT16Bone BuildingHelps shape the outer layer of your bones.
Wnt Family Member 16
WNT4Hormone BalanceHelps shape the female reproductive tract.
Wnt Family Member 4
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