Get a real answer from your own DNA
Pick a question that has nagged at you, and get a clear, plain-language answer read from your DNA. Already have a file from another company? Start with that. Want the whole picture? The complete Guides go deeper.
Your Circadian Rhythm can be working for you or against you.
Whose side is yours on?
Two circadian clocks from two different people. The same question, read from two different people's own DNA, gives a different answer, right down to the best hours to eat.
Your Answer Reports.
The DNA file you already have may power your Intrinsic Genomics Answer Reports. Pick your Answer Report, upload your file, and we'll let you know which ones your DNA file has the data for. We'll let you know what we can and cannot provide you with. If your file can power some but not all, you can complete an IG DNA Test to unlock the rest. If we cannot produce any reports from your file, you get a full refund.
“My body had been yelling at me my whole life. I just didn’t understand its language so I didn’t know what it was saying.”
Maria Herlihy, founder of Intrinsic Genomics
She built Intrinsic Genomics so no one waits decades for their own answers. Read her story →
No two Answers are alike
The same question gives two people completely different answers, read from their own DNA. Here is a real, scored comparison.
How it works
The same three steps power every Intrinsic Genomics Answer Report.
We read your DNA file
We read the DNA file you give us, whether it is one you already have or our own DNA test, and focus on the variants that have been studied for the question you asked.
We apply proprietary polygenic scores
Each finding is scored 0–100 using our proprietary polygenic scores, combining multiple well-studied variants weighted by published effect sizes.
You get a personalized Answer Report
Clear scorecards and plain-language recommendations you can act on with a health or wellness professional.
Get your whole body guides
When you want more than one answer, the Guides read your whole DNA file through a different lens each, scored on our proprietary Genetic Friction™ Score. The deepest Guides use our DNA test.
My Macronutrient Guide™
How you handle protein, carbs, and fats across three dimensions, plus a personalized macro calculator.
Explore the guide →My Micronutrients+ Guide™
How well your body manages 30+ vitamins, minerals, and supplements, with food-first guidance for each.
Explore the guide →My Nutrition Protocols Guide™
How your genes interact with popular diet, fasting, and exercise protocols, scored on Tolerance and Success.
Explore the guide →Meet your Genetic Friction™ Score
Every Answer uses the same scale. Think of it less like a grade and more like a resistance meter. A low score means your genes work with you; a higher score means they create obstacles worth paying attention to.
Built to be trustworthy
We curate the strongest research, connect it to your DNA, and translate it into an Answer you can actually use. Our design choices are simple, transparent, and deliberately conservative.
Evidence first
Every finding clears three filters: peer-reviewed research, a replicated effect, and clinically meaningful relevance. We separate “interesting” from “actionable.”
Polygenic, not single-gene
Each score combines several well-studied variants rather than one marker, so a single quirky finding can’t move the needle.
Answers, not data
We don’t hand you a spreadsheet of variants. Each Answer surfaces a few top priorities with specific, do-this-next steps in plain language.
Start with one answer from your DNA
Order your DNA test once and unlock personalized, evidence-first guidance you can use with your provider.
Take your pick of Answer ReportsWe recommend our DNA test: one blood draw gives us the deepest read of your DNA without the much higher cost of running your whole genome, and one sample covers all of your Guides and Answer Reports. Already had your blood drawn with us? You’re all set. Have a DNA file from another service? Start getting your answers quicker. We run your external file through a rigorous 12 step analysis to determine what we can do for you. Within a day of your upload we will let you know which Guides and Answer Reports we can satisfactorily produce. If we cannot produce a report or guide we are satisfied with, we refund you in full. If neither, add the one-time DNA test in your cart, and we can keep moving. One sample covers all of your reports and guides, now and in the future. Change your mind before your draw? Full refund.